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論文関連情報

Pharma GABA

  • Dietary Gamma-Aminobutyric Acid (GABA) Induces Satiation by Enhancing the Postprandial Activation of Vagal Afferent Nerves

  • Nakamura U, Nohmi T, Sagane R, Hai J, Ohbayashi K, Miyazaki M, Yamatsu A, Kim M and Iwasaki Y
  • Nutrients2022, 14, 2492

  • Exosome-Mediated Activation of Neuronal Cells Triggered by Aminobutyric Acid (GABA)

  • Inotsuka R, Udono M, Yamatsu A, Kim M and Katakura Y
  • Nutrients2021, 13, 2544

  • Intake of 200 mg/day of γ-Aminobutyric Acid (GABA) improves a wide range of cognitive functions: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

  • Yamatsu A, Nakamura U, Hossain MS, Horie N, Kaneko T, Kim M
  • Japanese Pharmacology & Therapeutics 2020, 48: 461-474

  • Improvement of memory and spatial cognitive function by continuous ingestion of 100 mg/day of γ-Aminobutyric Acid (GABA): A Randomized, Double-Blind, Placebo-Controlled Trial

  • Yamatsu A, Nakamura U, Hossain MS, Horie N, Kaneko T, Kim M
  • Japanese Pharmacology & Therapeutics2020, 48: 475-486

  • γ-Aminobutyric acid (GABA) activates neuronal cells by inducing the secretion of exosomes from intestinal cells

  • Inotsuka R, Uchimura K, Yamatsu A, Kim M, Katakura Y
  • Food & Function2020, 11: 9285-9290

  • Oral Supplementation Using Gamma-Aminobutyric Acid and Whey Protein Improves Whole Body Fat-Free Mass in Men After Resistance Training

  • Sakashita M, Nakamura U, Horie N, Yokoyama Y, Kim M, Fujita S
  • J Clin Med Res2019 Jun;11(6):428-434

  • γ-アミノ酪酸（GABA）の健常人に対する過剰摂取時の安全性の検討

  • 坂下 真耶、堀江 健二、岩城 佳津美
  • 薬理と治療2016 Nov;44(11):1639-44

  • GABAの睡眠改善機能

  • 山津 敦史、山下 裕輔
  • 薬理と治療2016 Sep;44(9):1277-9

  • Effect of oral γ-aminobutyric acid (GABA) administration on sleep and its absorption in humans

  • Yamatsu A, Yamashita Y, Pandharipande T, Maru I, Kim M
  • Food Science and Biotechnology2016 Apr;25(2):547-51

  • The Beneficial Effects of Coffee on Stress and Fatigue can be Enhanced by the Addition of GABA

  • Yamatsu A, Yamashita Y, Shibata M, Yoneyama M, Horie K, Horie N, Kim M, Yokogoshi H
  • 薬理と治療2015 Apr;43(4);515-9

  • Subchronic toxicity evaluation of γ-aminobutyric acid (GABA) in rats

  • Takeshima K, Yamatsu A, Yamashita Y, Watabe K, Horie N, Masuda K, Kim M
  • Food and Chemical Toxicology2014 Jun;68:128-34

  • Beneficial Action of GABA on Sleep and Frequent Night Urination in the Elderly

  • Yamatsu A, Yamashita Y, Horie K, Takeshima K, HorieN, Masuda K, Yamane T, Kim M
  • Japanese Pharmacology & Therapeutics2013 Oct;41(10):985-8

  • Reliving Occupational Fatigue by Consumption of a Beverage containing γ-Amino Butyric Acid

  • Kanehira T, Nakamura Y, Nakamura K, Horie K, Horie N, Furugori K, Sauchi Y, Yokogoshi H
  • Journal of Nutritional Science and Vitaminology2011 Apr;57(1):9-15

  • Effect of allowing to use paddock and administering γ-Amino acid for welfare of piglets

  • Nakamura K, Uetake K, Yoshida Y, Eguchi Y, Tanaka T
  • Animal Behaviour and Management2009 Mar; 45(1):9-18

  • Dietary γ-aminobutyric acid affects the brain protein synthesis rate in ovariectomized female rats

  • Tujioka K, Ohsumi M, Horie K, Hayase K, Yokogoshi H
  • J Nutr Sci Vitaminol2009 Feb; 55:75-80

  • Gamma-aminobutyric acid specifically inhibits progression of tubular fibrosis and atrophy in nephrectomized rats

  • Sasaki S, Tohda C, Kim M, Yokozawa T
  • Biol Pharm Bull2007 Apr;30(4):687-91

  • Dietary gamma-aminobutyric acid affects the brain protein synthesis rate in young rats

  • Tujioka K, Okuyama S, Yokogoshi H, Fukaya Y, Hayase K, Horie K, Kim M
  • Amino Acids2007 Feb;32(2):255-60. Epub 2006 Jun 7

  • Protective role of gamma-aminobutyric acid against chronic renal failure in rats

  • Sasaki S, Yokozawa T, Cho EJ, Oowada S, Kim M
  • J Pharm Pharmacol2006 Nov;58(11):1515-25

  • Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans

  • Abdou AM, Higashiguchi S, Horie K, Kim M, Hatta H, Yokogoshi H
  • Biofactors2006;26(3):201-8

Bonepep

  • Protective effect of egg yolk peptide on bone metabolism

  • Kim HK, Lee S, Leem KH
  • Menopause2011 Mar;18(3):307-13. doi: 10.1097/gme.0b013e3181f31b1f

Runpep

  • Effects of egg white-derived peptide intake on thermoregulatory response and energy metabolism during endurance exercise

  • Shirato M, Suga M, Yoshida Y, Kim M, Demachi K, Yoshida T
  • Journal of Physical Fitness, Nutrition and Immunology2008;18(1):28-38

HGP

  • Naturally Occurring Hair Growth Peptide: Water-Soluble Chicken Egg Yolk Peptides Stimulate Hair Growth Through Induction of Vascular Endothelial Growth Factor Production

  • Nakamura T, Yamamura H, Park K, Pereira C, Uchida Y, Horie N, Kim M, Itami S
  • Journal of Medicinal Food2018 Jul;21(7):701-708

HAS-II

  • Intake of Chicken Leg Peptides Improves Quality of Life by Relieving Mild Knee Pain ―A Randomized, Double‒blind, Placebo‒controlled Trial, Additional Analysis―

  • 山田裕晃、山下裕輔、高良毅
  • Jpn Pharmacol Ther2022, vol.50, Issue 9, 1677 - 1687

  • Intake of chicken leg peptides improves quality of life by relieving mild knee pain -A Randomized, Double-Blind, Placebo-Controlled Trial-

  • Yamada H, Hossain MS, Sakashita M, Yamatsu A, Takara T, Kim M
  • Japanese Pharmacology & Therapeutics2020, 48: 487-496

  • Study of the cartilage matrix production-promoting effect of chicken leg extract and identification of the active ingredient

  • Yamada H, Nakamura U, Nakamura T, Uchida Y, Yamatsu A, Kim M
  • Nutrition Research and Practice2019 Dec;13(6):480-487

  • Safety evaluation of excessive intake of chicken leg extract (HAS-II®) in healthy adult subjects —A randomized, placebo-controlled, double-blind study—

  • Nakamura T, Sakashita M, Yamatsu A, Kim M, Iwaki K
  • 薬理と治療2019; 47(11):1913-1917

Cerepron

  • Safety evaluation of excessive intake of heat-induced yeast extract (Cerepron®) in healthy subjects

  • Jasni NN, Nakamura U, Kosasa H, Kim M
  • 薬理と治療2019; 47(1):115-119

  • Inhibition of Melanin Synthesis and Skin Whitening Effect by Heat-induced Yeast Extract (Cerepron®)

  • Sakashita M, Yamashita Y, Harada S, Kim M
  • 薬理と治療2016 Feb;44(2):221-6

iHA

  • Egg Yolk Peptide (iHA) Induces Hyaluronic Acid Production of the Chondroprogenitor Cells

  • Aosasa M, Watabe K, An J, Horie N, Masuda K, Kim M, Murata H, Yamane T, Zhu X, Uchino T, Asai K
  • Japanase Pharamacology & Therapeutics2012 Oct;40(10):897-900

IgY

  • Immunoglobulin: A Natural Way to Suppress Helicobacter pylori in Humans

  • Abdou AM, Ahmed MME, Yamashita Y, Kim M
  • Health2014 Mar;6:781-91

  • Suppressive effect of functional drinking yogurt containing specific egg yolk immunoglobulin on Helicobacter pylori in humans

  • Horie K, Horie N, Abdou AM, Yang JO, Yun SS, Chun HN, Park CK, Kim M, Hatta H
  • J Dairy Sci2004 Dec;87(12):4073-9

Catechin

  • Therapeutic potential of (-)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats

  • Yamabe N, Yokozawa T, Oya T, Kim M
  • J Pharmacol Exp Ther2006 Oct;319(1):228-36

  • Activity of (-)-epigallocatechin 3-O-gallate against oxidative stress in rats with adenine-induced renal failure

  • Nakagawa T, Yokozawa T, Sano M, Takeuchi S, Kim M, Minamoto S
  • J Agric Food Chem2004 Apr 7;52(7):2103-7

  • Effects of green tea polyphenol on cognitive and acetylcholinesterase activities

  • Kim HK, Kim M, Kim S, Kim M, Chung JH
  • Biosci Biotechnol Biochem2004 Sep;68(9):1977-9

Banafine

  • Effects of Banafine, a fermented green banana-derived acidic glycoconjugate, on influenza vaccine antibody titer in elderly patients receiving gastrostomy tube feeding

  • Horie K, Hossain MS, Kim Y, Ishida A, Kon R, Yamatsu A, Kishima M, Nishikimi T, Kim M
  • Journal of Food Science2021, 86: 1410-1417

  • The potency of a novel fermented unripe banana powder as a functional immunostimulatory food ingredien

  • Horie K, Hossain MS, Morita S, Kim Y, Yamatsu A, Watanabe Y, Ohgitani E, Mazda O, Kim M
  • Journal of Functional Foods2020, 70: 103980

セラミノール

  • Efficacy and Safety of Oral Administration ofWine Lees Extract (WLE)-Derived Ceramides and Glucosylceramides in Enhancing Skin Barrier Function: A Randomized, Double-Blind, Placebo-Controlled Study

  • Angga Sanjaya, Akiko Ishida, Xuan Li, Yugweng Kim, Hiroaki Yamada , Takashi Kometani, Yusuke Yamashita and Young-il Kim
  • Nutrients2024, 16, 2100

LipiSmart

  • Ameliorating Effects of Pulverized Sesame Powder Containing Lignocellulose and Resistant Protein on Postprandial Triglyceride Elevation

  • Hiroaki Yamada, Sayo Morita, Xuan Li, Yusuke Yamashita, Akiko Ishida, Takashi Kometani, Toma Furuta, Young-Il Kim
  • Journal of Food and Nutrition Research2023, Vol. 11, No. 8, 540-548

  • The Attenuating Effects of Insoluble Dietary Fiber and Resistant Proteins Derived from Pulverized Sesame Powder (LipiSmart®) on Postprandal Triglyceride Absorption

  • Hiroaki Yamada, Sayo Morita, Xuan Li, Chiharu Hatta, Toma Furuta, Wakana Oota, Yusuke Yamashita, Young-Il Kim
  • Jpn Pharmacol Ther2023, vol.51, No.2, 203-208

  • 微粉砕脱脂ごま粉末（リピスマート®）の健常人に対する安全性の検討

  • 山田裕晃、井出将博、山下裕輔、松岡成郎、山路之洋、山﨑義光
  • Jpn Pharmacol Ther2022, vol.50, No.8, 1369-1380

  • 微粉砕脱脂ごま粉末（リピスマート®）の日本人健常人に対する長期安全性の検討 -プラセボ対照無作為化二重盲検並行群間比較試験-

  • 山田裕晃、森田沙代、井出将博、山下裕輔、金英一、古田到真、大田和香奈、福田正博
  • Jpn Pharmacol Ther2023, vol.51, No.6, 841-851

Other

  • Antiglycation Effect of Jabuticaba (Plinia cauliflora) and Its Potential Role in Delaying Cataract Formation in Streptozotocin-Induced Diabetic Rats

  • Arif Yanuar Ridwan, Yuki Shimozu, Nikesh Narang, Takashi Kometani, Yusuke Yamashita and Young-Il Kim
  • Nutraceuticals2024, 4,363–372.

  • Effects of Free Linoleic Acid and Oleic Acid in Sesame Meal Extract as Pancreatic Lipase Inhibitors on Postprandial Triglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Volunteers

  • Xuan Li, Hiroaki Yamada, Sayo Morita, Yusuke Yamashita, Youngil Kim, Takashi Kometani,Nikesh Narang, Toma Furuta and Mujo Kim
  • Nutrients2023, 15, 1748.

  • Free Linoleic Acid and Oleic Acid Reduce Fat Digestion and Absorption In Vivo as Potent Pancreatic Lipase Inhibitors Derived from Sesame Meal

  • Xuan Li, Sayo Morita, Hiroaki Yamada, Keita Koga, Wakana Ota, Toma Furuta, Atsushi Yamatsu, and Mujo Kim
  • Molecules 2022, 27, 4910.